This report provides a useful tool for the standardisation of a method to identify and evaluate cities in respect of several societal city challenges. Such a tool will allow practitioners to be able to examine these challenges in a simple way with accurate information about how these challenges might affect cities and how and why cities might come to understand urban vulnerability as soon as possible. Although its title is “Climate Change Challenge Catalogue”, its approach was redefined to cover a wider definition of “challenge”. This was due to the fact that nature-based solutions are solutions to a number of societal challenges and not only climate change issues. For this reason, a brief subset of challenges in the form of cards has been developed to form this catalogue, including their definition as well as key indicators and methods for assessing the possible impacts to be achieved through the use of nature-based solutions in cities.