Nature underpins all economic activities and human well-being. It is the world’s most important asset. Yet humanity is destroying biodiversity at an unprecedented rate, posing significant but often overlooked risks to the economy, the financial sector and the well-being of current and future generations. This report provides the latest findings and policy guidance for G7 and other countries in four key areas: measuring and mainstreaming biodiversity; aligning budgetary and fiscal policy with biodiversity; embedding biodiversity in the financial sector; and improving biodiversity outcomes linked to international trade. The report shows how Finance, Economic and Environment Ministries can drive the transformative changes required to halt and reverse the loss of biodiversity. This Policy Paper was prepared as an input document for the United Kingdom Presidency of the G7 in 2021.